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KMID : 0895820160260040009
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Journal of Oriental Rehabilitation Medicine
2016 Volume.26 No. 4 p.9 ~ p.21
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Effects of the Herbal Medicine in Animal Models for Treatment of Sciatic Nerve Impairment: A Review of Animal Study Reports
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Lee Chi-Ho
Lee Jae-Eun
Choi Young-Jun
Lee Eun-Jung
Oh Min-Seok
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Abstract
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Objectives : This study is to review the effect of herbal medicine on treatment of sciatic nerve injury induced animal models reported in domestic & foreign journals.
Methods : 5 electronic databases (Pubmed, CAJ, RISS, Oasis, Koreantk) were searched with term as sciatic nerve injury, and animal study reports on sciatic nerve impairment with herbal medicine treatment were extracted.
Results : 31 articles were reviewd. All studies used SD rat. 26 studies used crush injury at the sciatic nerve using haemostatic forcep and 5 studies used sciatic nerve transection. 15 studies used single herb extract and 16 studies used complex herb medicine. Angelica gigantis radix was the most frequently used herb. Each study showed significant changes of improvement indicators from sciatic nerve impairment.
Conclusions : Various herb medicine are expected to have positive effects on sciatic nerve impairment.
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KEYWORD
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Sciatic nerve impairmen, Herb medicine, Animal model, Review
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